Official logo and claim of anti-wrinkle active ingredient ARGIRELINE® peptide, by Lipotec

A breakthrough in cosmetic technology as an alternative to Botulinum Toxin, topically targetting the same wrinkle-formation mechanism in a very different way.

  • ARGIRELINE® peptide (Acetyl Hexapeptide-8) is a replica of the N-terminal end of SNAP-25 and competes with the natural protein for a position in the SNARE complex, thereby destabilizing its formation without breaking any of its components.
  • When the SNARE complex is slightly destabilized, the vesicle cannot release neurotransmitters and the muscle contraction is attenuated leaving the muscle relaxed as a consequence. Formation of lines and wrinkles is prevented in this way.


Nothing is more attractive
than a relaxed face

in just 1 week

With a powerful lifting effect, a solution with ARGIRELINE® peptide (2%) reduced in vivo expression wrinkles in just 1 week (volume by 20.6% and length by 15.9%). Other parameters used to describe wrinkles, like roughness and depth, were also decreased as proved in further clinical tests.

Go to product information
In vivo efficacy results showing the effect of Lipotec’s ARGIRELINE® peptide on wrinkle volume and length
In vivo efficacy results showing the effect of Lipotec’s ARGIRELINE® peptide on wrinkle volume and length

Images of the expression wrinkles of a volunteer before and after 7 days.

A widely known solution for 1st to appear wrinkles

"The number of wrinkles decreased after treatment and the existing ones were less deep, especially in the area around the eyes"Victoria Moral, 43 years

"The reduction of expression wrinkles was notorious for me and for those around me."Pilar Soriano, 56 years

"I noticed my skin more elastic and the crow's feet decreased visibly. I am delighted!"Maria José López, 48 years

around the world

Did you know…?
… that ARGIRELINE® peptide


Lipotec develops active ingredients for the personal care industry and supplies them to leading cosmetic product manufacturers and brand owners worldwide.

The information contained in Lipotec's intranet is exclusively addressed to personal care industry professionals and access to specific data will be granted according to user profile (customers, distributors, consultants, media...).